Science Journal: Chimeras Exist, What if Some Turn out too Human?


Such a chimera could bring important scientific benefits. The SCID-hu mouse, though it hasn’t yielded a cure for AIDS, has been “a very valuable animal model,” says Ramesh Akkina of Colorado State University, Fort Collins, who directs a lab that uses this part-human mouse. “It has human T cells circulating, which will allow us to test gene therapy for AIDS” in a way that will be more relevant to patients than all-animal models.